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Seek urgent medical assessment for severe or persistent abdominal pain, repeated vomiting, signs of dehydration, trouble breathing, swelling of the face or throat, fainting, or symptoms of very low blood sugar

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In this trial, the average HbA1c level dropped by up to 2.1% with a 45 mg dose of orforglipron, while the placebo group showed a decrease of only 0.4%

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