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Specifically, the relative risks were reduced by approximately 37% for Alzheimers disease, 41% for Lewy body dementia, and 56% for vascular dementia

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A newer ex vivo human arterial tissue study found concentration-dependent vasorelaxation in human internal mammary artery rings, with much of the effect appearing to involve an endothelium-dependent nitric oxide pathway (Journal of Clinical Medicine)

219,220 Anthocyanins reduce the phosphorylation of NF-B p65 and downregulate the expression of NF-B target genes and proteins, such as COX-2 and iNOS, which improves DSS-induced colitis

This lets the body adjust, minimizes side effects, and still delivers the full benefits