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More serious but less common side effects can include swelling in the hands or feet, increased blood sugar, allergic reactions, or numbness and tingling

Mitochondrial biogenesis and dynamics in the developing and diseased heart

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In addition, polymeric nanovesicles Gem/Sul-NP which simultaneously encapsulate and deliver gemcitabine and the prolyl isomerase Pin1 inhibitor sulfopin, can effectively remodel the immunosuppressive TME and significantly increases the infiltration of CD8 IFN T cells when combined with anti-PD-1 therapy (190)