The Clinic Takeaway: What AOD 9604 Means for South Florida Patients AOD 9604 is not a weight loss miracle
The Bottom Line The extent to which your daily drink contributes to inflammation and associated disease risk may come down to what youve eaten, how much youve slept, how hydrated you are, the state of your gut, and of course, how much (and how often) you drink
this is a protocol born from countless hours of lab work and an unwavering commitment to scientific validity
Effects of gaseous and solid constituents of air pollution on endothelial function
Nitric oxide in mucosal immunity
(2000), Horm Res 53(Suppl 3), PubMed 10971106 Statistics from preclinical literature AOD-9604 = modified fragment of hGH 177191 + N-terminal Tyr (sequence Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe), molecular weight 1815.1 Da Developed at Metabolic Pharmaceuticals (Australia) based on the work of professor Frank Ng (Monash University) in the 1990s Standard experimental dose in obesity clinical trials: 1 mg/day subcutaneously (Phase 2b, Heffernan et al.) Mechanism: stimulation of 3-adrenergic receptors in adipose tissue, increased lipolysis and fatty acid oxidation without activation of the hGH receptor (no IGF-1 increase) Phase 2b clinical trial (2007, 300 patients): weight reduction ~2.8 kg vs placebo over 12 weeks FDA status: NDI rejection (2014) as a dietary supplement