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finally, in terms of limitations, it highlights the heterogeneity in evidence [e.g., variations in Omega-3 dosing across RCTs (65)] and population-specific biases [e.g., vitamin D studies focusing on IBD patients (169)]

Notably, the G/D-CuP group demonstrated the lowest CD86/CD206 ratio, further indicating a promoted transition from the M1 to M2 phenotype (Supplementary Fig

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