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doi: 10.1016/j.ghir.2020.101319 71 SnyderDKClemmonsDRUnderwoodLE

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Vitamin C is a reducing agent capable of rapidly eliminating reactive oxygen species (ROS), it also works as a pro-oxidant antibacterial molecule, potentially altering the antimicrobial efficacy of some antibiotics by two proposed mechanisms: I- the transfer of vitamin C into bacterial cells, which results in the synthesis of H2O2 and, as a result, ROS

Hoerr, F

Receptor density studies show that internalized MC4R begins returning to the cell surface within 48-72 hours of agonist withdrawal, but full functional recovery to baseline responsiveness takes 5-7 days

Hum Exp Toxicol