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A diferencia de los anlogos selectivos, el Melanotan II es un agonista no selectivo de los receptores de melanocortina, activando MC1R, MC3R, MC4R y MC5R, lo que explica su doble perfil de efectos sobre la pigmentacin (va MC1R) y sobre el sistema nervioso central (va MC4R)

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In mitigating oxidative stress, glucose metabolism is rewired to the PPP that operates parallel to glycolysis to maintain redox homeostasis by generating ribose-5-phosphate and NADPH [11]