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Deiodinases and their intricate role in thyroid hormone homeostasis

These alterations contribute to cognitive decline as well as to neuropsychiatric symptoms such as apathy and depression, which are frequently observed in patients [2426]

Noise reduction strategies in metagenomic chromosome confirmation capture to link antibiotic resistance genes to microbial hosts

Investigation of small-molecule modulators in metabolic pathway regulation

However, unlike FASD in which ethanol induces a retinol deficiency through substrate competition, a retinoic acid deficiency in ASD is more likely to involve mutations associated with ALDH s, resulting in an accumulation of retinal and a much lower production of retinoic acid

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