In contrast, the EC 50 of 0.08 M for protecting against radiation-induced glutathione changes established in this study equates to a 26 ng/mL concentration
In all cases, mice were housed in groups of 4 or 5 in a temperature-controlled room (23C) with lights on at 07:00 h and off at 19:00 h and had free access to tap water and laboratory chow
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Later work examined NNMT inhibition combined with dietary changes in obese mice, reporting reductions in body weight, fat mass, and hepatic fat, alongside shifts in gut bacterial populations
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