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Intervention studies have shown that weight reduction in PwO through caloric restriction alone or in combination with low-impact aerobic exercise results in increased levels of BTMs and decreased BMD values [29, 30]

Collagen and ECM-Related Genes ECM plays a central role in maintaining connective tissue integrity, and several collagen-related genes have been implicated in hEDS

Drugs from the GLP-1RA group targeting the GLP-1R, reduce damage caused by hypoperfusion through the interaction of pleiotropic pathways and signaling cascades, including those involved in mutual regulation of the gut and brain, thereby opening up new prospects for the treatment of neurocognitive disorders

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Zhao J, Redell JB, Moore AN, Dash PK

The therapeutic implications of tea polyphenols against dopamine (DA) neuron degeneration in parkinsons disease (PD)