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The peptide goes to the fat tissue, tells it to release its stored energy, and prevents it from restocking

When the permeability of the mitochondrial membrane increases, ROS that are produced by the METC in mitochondria can be released into the cytosol and induce inflammation via signal transduction or toxic destruction of biological macromolecules [17]

In total, 20 cell clusters were identified using a principal component analysis (PCA)based approach and projected by a Uniform Manifold Approximation and Projection (UMAP) onto a two-dimensional plot (Fig 3A)