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Liraglutide : It causes less severe stomach issues but needs daily injections, which can sometimes lead to irritation at the injection site

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Cardiovasc Diabetol (2019) 18(1):46

GLP-1 Medications with a simple generic name of "semaglutide", "liraglutide", "tirzepatide", "dulaglutide", "exenatide", "exenatide microspheres", or "insulin degludec/liraglutide" and at least one of: A pharmaceutical class of "ANTI-OBESITY GLUCAGON-LIKE PEPTIDE-1 RECEP AGONIST" or "ANTIHYPERGLYCEMIC - INCRETIN MIMETICS COMBINATION" A pharmaceutical class that contains "GLP-1" A pharmaceutical subclass that contains the text "GLP-1"

[1] [2] Acid reflux or gastroesophageal reflux symptoms may occur in some patients taking semaglutide, though the exact incidence varies by product, dose, and individual factors