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In another example, Ryan et al

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The studies were conducted in individuals with conditions with low glutathione such as HIV (6, 7) , Type 2 Diabetes Mellitus (T2DM) (8) , and autism (9)

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For example, it has been demonstrated that mHtt inhibits the delivery of the mitophagy receptor to autophagosomes, while simultaneously blocking autophagosome formation, disrupting mitophagy initiation, and affecting autophagosome translocation to lysosomes (Wong and Holzbaur, 2014)

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