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Method of Action : Stimulants increase the amounts of dopamine, norepinephrine, and sometimes serotonin in the synaptic cleft through various mechanisms

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Striatal dopamine levels reached 7.14 1.19 ng/mg tissue, alongside significant increases in metabolites such as homovanillic acid (3.59 0.51 ng/mg compared to 1.93 0.43 ng/mg in controls) and 3,4-dihydroxyphenylacetic acid (13.43 1.62 ng/mg compared to 8.97 1.49 ng/mg in controls)

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And GPX4-mediated ferroptosis was involved in the neuroprotective effect of lapatinib in epileptic seizures (Figure 8)