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High-dose supplements of vitamins C and E, low-dose multivitamins, and the risk of age-related cataract: a population-based prospective cohort study of men

Importantly, for many patients, heartburn and other gastrointestinal symptoms diminish over time as physiological adaptation occurs, though a subset of patients may experience persistent symptoms requiring intervention or medication discontinuation

Adding nutrients that support proper absorption, distribution/digestion, metabolism and elimination (ADME), and thyroid function, such as magnesium , selenium , thiamine , and zinc

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Adrenal suppression is more likely with high doses or prolonged use

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