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Citrulline may be more effective than direct L-arginine supplementation due to superior bioavailability, bypassing gut metabolism to raise blood arginine levels by 30-35%

It can also improve the flow of blood to the brain and boost memory, particularly in people who are elderly

Overall, the science is intriguing, though more research is needed

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Age and sex differences in plasma homocysteine, choline and betaine status in Seychellois children and young adults

A Phase I trial confirmed that just 5 low-dose subcutaneous injections produced measurable pigmentation changes in the face, upper body, and buttock (Dorr et al., 1996)