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The investigation specifically showed that these drugs did not increase the risk of any fractures, confirming their safety profile in clinical practice ( 4.6 Ophthalmological effects 4.6.1 Glaucoma GLP-1R agonists exhibit anti-inflammatory and neuroprotective properties, suggesting they could also be beneficial in neurodegenerative diseases ( A recent registry-based case-control study, summarized in Table 2 , involving 1,961 patients found that the use of GLP-1R agonists is linked to a lower risk of glaucoma (Sterling et al., 2021 ( Table 2 Clinical studies elucidating the use of antidiabetics against glaucoma

Discuss your concerns with your provider to weigh risks, benefits, and possible alternatives for managing weight or diabetes

GLP-1 medications work by mimicking a natural hormone that helps regulate blood sugar and appetite

doi: 10.1371/journal.pone.0058784 [DOI] [PMC free article] [PubMed] [Google Scholar] 210.Cai HY, Hlscher C, Yue XH, et al

Higher doses are subject to the regulations for Therapeutic Use Exemptions (TUE)