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9 The original Diabetes Prevention Program (DPP) trial, published in 2002, showed that intensive lifestyle change (a 7% weight loss target plus 150 minutes of physical activity per week) reduced the incidence of type 2 diabetes by 58% over 3 years

Medicare: Federal law has historically excluded weight-loss medications from Medicare Part D coverage

Whitworth, J

In the STEP-1 trial of 1,961 adults (Wilding and colleagues, Once-Weekly Semaglutide in Adults with Overweight or Obesity, New England Journal of Medicine, 2021), participants on semaglutide 2.4 mg lost an average of 14.9 percent of their body weight at 68 weeks, compared to 2.4 percent on placebo

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