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The Lancet Gastroenterology & Hepatology

The prescribing information for both medications specifically advises against combining GLP-1 receptor agonists

Starting doses may be 10 milligrams or 20 milligrams a day

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Patients should be monitored to determine: Whether the treatment is producing meaningful progress Whether the dosage needs to be adjusted Whether side effects are developing Whether another treatment would be more appropriate Whether changes to nutrition or activity are needed Current health conditions, family medical history, other medications, potential drug interactions, expected benefits, possible side effects, and cost should all be considered before selecting a weight loss medication

The makers of Ozempic, Wegovy and Mounjaro are racing to prove that the incredibly popular drugs have health benefits beyond weight loss and diabetes