Avoid high-dose stimulant laxatives, especially castor oil, as they can cause severe cramping and electrolyte loss in combination with semaglutide's reduced gut transit
Anti-interleukin-21 antibody and liraglutide for the preservation of -cell function in adults with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled, phase 2 trial
Several ophthalmologists and public health advocates are now urging the agency to require a black box warning on semaglutide drugs, including Ozempic, Wegovy, and Rybelsus, in light of mounting evidence linking them to nonarteritic anterior ischemic optic neuropathy (NAION)
(2025) GLP-1RA-induced delays in gastrointestinal motility: Predicted effects on coadministered drug absorption by PBPK analysis Wissam Ghusn, et al
Its really just related to whether or not they can get a prescription from a prescriber. The future of regulations around peptides may also somewhat mirror how dietary supplements are currently regulated, suggested Dr
The SURPASS-2 trial directly compared the two for type 2 diabetes and found tirzepatide superior at all dose levels