Serum/cerebrospinal fluid (CSF) and positron emission tomography (PET) did not show significant improvement in amyloid plaques, tau pathology, or neuroinflammatory markers
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Fibroblasts secrete inflammatory cytokines and chemokines, such as tumor necrosis factor-alpha (TNF-), IL-1, and chemokine (C-X-C Motif) ligand 8 (CXCL8), contributing to the inflammatory environment
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Their crosstalk is essential for the development of various diseases, including obesity, alcoholic liver disease and other metabolic diseases [52, 53]
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