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Statistics and reproducibility Where applicable, protein abundance and fluorescence intensities were normalized to the values calculated for the controls as described in each figure legend and analyzed with bilateral Students T -tests (two-tailed distribution and homoscedastic) on Excel (Microsoft Office 365)

doi: 10.1016/0142-9612(95)00310-X

Some patients eventually transition to sublingual B12 with occasional booster injections

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Magnetic resonance imaging (MRI) can directly assess changes in muscle mass and composition, including fat infiltration