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Increasing muscle creatine stores supports short bursts of high-intensity movement

The GIP receptor activation adds metabolic effects that pure GLP-1 agonists do not provide, including potential benefits for bone formation and gut motility that may actually buffer against certain gastrointestinal side effects

When people lose weight quickly, they typically lose a combination of fat mass and lean body mass

Four published studies showed no pancreatitis effects including one in which the pancreas of rats, mice and monkeys showed no change with liraglutide at concentrations 60 fold higher than used in humans for up to two years (86)

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Most payers evaluate any drug of any drug class based on safety, efficacy and cost, he said