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For a 5mg/mL formulation in a standard insulin syringe: 20 units equals 0.2mL, which delivers 1mg of tirzepatide 50 units equals 0.5mL, which delivers 2.5mg of tirzepatide 100 units equals 1.0mL, which delivers 5mg of tirzepatide For a 10mg/mL formulation: The numbers change again for 20mg/mL and 30mg/mL concentrations
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The final model included log-normal inter-individual variability model for bioavailability (F), and a proportional residual error model
Diabetologia 51 , 15521553 (2008)