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This study identified IL-4 as a key tumor-derived factor that drives macrophage polarization, particularly promoting the MARCO-expressing macrophage subset in the ovarian tumor microenvironment

Downstream targets of VHL/HIF- Signaling in renal clear cell carcinoma progression: mechanisms and therapeutic relevance

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This distinction is required on the labels of research chemicals and is what exempts them from regulation under parts 100-740 in Title 21 of the Code of Federal Regulations (21CFR)