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Novo Nordisk's own clinical trial found that patients on the higher Wegovy dose lost an average of 47 pounds, which the company says is clinically consistent with Zepbound's results in Lilly's own trial data

These findings open a new frontier in personalized neuroendocrine therapy, particularly relevant for postmenopausal women, who bear a disproportionate burden of AD and are often underrepresented in clinical trials

[33] demonstrated that insulin treatment promoted the differentiation of human Th cells toward an anti-inflammatory Th2 phenotype

This shift explains why blood sugar management becomes more challenging and why carbohydrate tolerance seems to diminish with age

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