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NNMT inhibition increases adipose [S-adenosylmethionine (SAM)] and [Nicotinamide adenine dinucleotide (NAD+)] levels As youll discover later on in this article, theres a good reason why increased production of SAM and NAD+ within fat cells is beneficial

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The article adds that a qualified provider must also evaluate kidney function, gastrointestinal history, thyroid status, and cardiovascular risk profile beforehand

doi: 10.1016/j.biopsych.2016.08.024 95 KhannaSToshPK

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