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Following administration, Modified GRF(1-29) produces peak effects within 15-30 minutes, with duration of elevated GH typically lasting 2-3 hours based on GHRH analog pharmacology

Depending on their subtype, TAMs can produce either pro-inflammatory cytokines (e.g., IL-1 and IL-6) or anti-inflammatory cytokines (e.g., IL-4 and IL-10), thereby modulating the cytokine profile and shifting the tumor microenvironment toward either tumor suppression or tumor promotion (91)