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Acknowledgements This study was approved by the Alfred Hospital Ethics Committee (project number 463/18) and the Australian Institute of Health and Welfare Ethics Committee (EO2018/5/501)

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The cyclic lactam structure that defines MT-II has served as a template for subsequent melanocortin-receptor probe development, including the receptor-selective antagonist series reported by Hruby and colleagues in 1995 using bulky aromatic substitutions at position 7 [8]

10.3389/fimmu.2020.01748 Front Immunol

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