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Thus, it was hypothesized that PFF-induced toxicity is, at least to a certain degree, mediated by glutathione depletion, which becomes critical when the cell accumulates an extensive amount of aggregates [86]

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The GO@GSH-FA treatment group displayed the lowest fluorescence intensity, suggesting the most substantial reduction in ROS levels among all treatment groups

doi: 10.1007/s00394-014-0706-z [DOI] [PubMed] [Google Scholar] 32.Kleinman WA, Richie JP Jr

Twenty participants with obesity and at least 10% liver fat received either 25mg CB4211 via daily subcutaneous injection or placebo for 28 days

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