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Why Weight Regain Occurs After Stopping Treatment Weight regain after discontinuing weight loss injections is a multifactorial process involving physiological, metabolic, and behavioural mechanisms

The medication loses its efficacy and potency beyond the expiration date, impacting its effect on the body

It is also suitable for individuals with weight-related health issues, such as type 2 diabetes

Analogous to the pancreatic islet, adipocytes adapt during pregnancy and lactation, when PRL values may exceed 200 g/L, including neural (dopaminergic) changes that increase appetite, food intake, and redistribute nutrients, lipid storage from abdominal tissues to mammary glands (54)

For non-diabetic individuals struggling with obesity, these medications can support significant weight loss , with clinical trials showing an average reduction of 10-15% of body weight while also improving metabolic health and blood sugar regulation

Fermented foods: Yoghurt, kefir, sauerkraut, and miso provide probiotics that improve gut motility