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Transcriptomic profiling identified more than 5,400 differentially expressed genes in the liver and over 8,000 in adipose tissue, indicating extensive remodeling of inflammatory and metabolic pathways

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Eighteen studies examined the effect of GLP-1RAs on weight loss, glucose control and mental illness outcomes in adults with a severe mental disorder, such as major depressive disorder, bipolar effective disorder, schizophrenia spectrum disorders, and alcohol use disorder