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Water Intoxication or Electrolyte Disturbances:Possible if used inappropriately

This guide covers the technical specifications of shelf life for both unopened and opened vials, the science of benzyl alcohol degradation, and the visual indicators of a compromised solution

(PubMed) Hutto BR

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For example, the surveyed incidence of self-reported ethanol-induced flushing reactions in Scandinavians living in Copenhagen as well as Australians of European descent is about 16% in individuals homozygous for the "normal" ADH1B gene but runs to ~23% in individuals with the ADH1-Arg48His SNP variant