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The interaction between the Gly-His-Lys peptide and fibroblasts is believed to potentially initiate a cascade of biological events leading to the synthesis of collagen, thereby playing a potential role in the mechanisms of tissue repair and regeneration

Heres what the literature shows and where the gaps remain

J Orient Neuropsychiatry 2004;15:2336

(PubMed) Moyle GJ, Sadler M

Effects of adenosylmethionine and NADPH on the equilibrium between active and inactive forms of the enzyme and on the kinetics of approach to equilibrium

In order to ensure that these changes in DHA sensitivity were not due to altered heme levels, we measured heme levels in PfMRP1-mutant and DD2 wildtype parasites and found no differences (Supp Fig 3D)