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Its definitely a smart thing to avoid with sensitive skin (and fragrance of any type - natural is just as allergic as synthetic, if not worse!)

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Cell 19 , 26732680 (2008)

10.1016/j.bcp.2004.05.032 Biochem

Glutathione is a very strong antioxidant, partly because high concentrations can be found in every cell in the body

At the same time, increased levels of inflammatory molecules, such as LPS from harmful bacteria, can lead to systemic-wide inflammation (Obrenovich et al., 2020)