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This is why simply feeding more B12-rich food rarely solves the problem

Efficacy and safety of once-weekly dulaglutide versus insulin glargine in mainly Asian patients with type 2 diabetes mellitus on metformin and/or a sulphonylurea: A 52-week open-label, randomized phase III trial

Weeks 6-12: Most significant weight loss begins during this period

Drugs Today (Barc) 2014;50(10):665678

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While neither source links dehydration to vaginal dryness specifically, systemic dehydration can plausibly worsen mucosal dryness and irritation symptoms in susceptible individuals, particularly where baseline genitourinary syndrome of menopause or vulvar dermatoses exist