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Notably, this reduction of the RNF213(371-5207) protein level was abolished, when either the catalytically inactive IpaH1.4 C368A mutant or the isolated NEL domain of IpaH1.4 was co-expressed with RNF213(371-5207), or when cells were treated with the proteasomal inhibitor MG132 (Fig
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At your consultation, well review your health history, ask about your goals, and walk you through which options are appropriate for you
