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Programmed cell death and Bcl-2 protection in very low oxygen
Copper in its metallic state has no effect on the skin and it becomes a potential irritant or allergen when it is corroded to become soluble through the action of exudates encountered on the skin surface, or in a relatively corrosive physiological environment such as the oral cavity or the uterus 3
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Oral administration remains the preferred option due to its convenience, high compliance, and strong patient acceptance
Mar 21 2000;2(2):73-77
Down-regulation Down-regulation is the reduction of receptor number that may result from receptor internalization followed by their degradation, or decrease in receptor synthesis
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