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Neurite outgrowth inhibitor or Nogo belongs to the reticulon 4 (RTN4) protein families, which consists of three major splicing isoforms (NogoA, Nogo-B, and Nogo-C) with distinct expression patterns that binds to NgR receptors [217, 218]

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Nevertheless, downstream analyses identified reproducible differences in specific metabolites that were consistently associated with ASD status within this cohort