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doi: 10.1016/j.neurobiolaging.2016.03.005 13 CristofanoA.SapereN.La MarcaG.AngiolilloA.VitaleM.CorbiG.et al

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although the risk was increased with concomitant SU therapy [11]

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This pharmacological profile creates a dose-dependent weight loss curve that, in clinical trials, reached 24.2% at the 12mg weekly dose over 48 weeks and an astonishing 28.7% at 12mg over 68 weeks in the TRIUMPH-4 phase 3 trial