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Protein Sci 18(5):980993 Rover L Jr, Kubota LT, Hehr NF (2001) Development of an amperometric biosensor based on glutathione peroxidase immobilized in a carbodiimide matrix for the analysis of reduced glutathione from serum

The first stage involves oxidation of the heme using first hydrogen peroxide molecule to form an oxyferryl species in which one oxidation equivalent is taken off from the iron and one from the porphyrin ring to make a porphyrin cation radical (reaction 2)

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Phytotherapy Research, 33 (12), 30903111

Hepatic benefits include reduced oxidative stress, inflammation, and improved liver enzyme profiles (ALT, hsCRP), as well as enhanced antioxidant enzyme levels, thereby protecting against acute liver injury