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c) In a clinical trial involving patients with osteoporosis, BPC-157 supplementation led to improvements in bone density and calcium metabolism markers, indicating its potential as an adjunctive therapy in calcium imbalance disorders

Since AAVs have been found to integrate within DSBs with high frequency [152], the coupling of CRISPR-Cas9 with AAVs as the delivery vector must be carefully evaluated before clinical translation [58, 153]

Tian, S., Huajun, W