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Study findings revealed that once-weekly subcutaneous semaglutide showed the largest estimated effect on body weight and several metabolic markers, identifying the GLP-1 RA as a highly promising intervention for future clinical trials in psychiatric populations, although comparative rankings remain uncertain because the evidence base was small, heterogeneous, and largely indirect

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GRX1-/- mice exhibit attenuated LPS-induced cytokine release (IL-1 and TNF-) and macrophage dysfunction, suggesting the dual role of GRX1 in the regulation of inflammation (90)

"When one has a decreased appetite, they may think that they do not need any insulin, and if [insulin is] held or dosed sub-optimally, it could theoretically increase the risk of DKA," said Dr

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