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38 One classic metabolic reprogramming in tumors is the Warburg effect, 36,39,40,41 which is associated with lactate production

The ZDHHC7 palmitoylates NLRP3 on Cys126, and thus mutation of NLRP3 Cys126 would disrupt its localization in the TGN as well as the recruitment and oligomerization of ASCs, inhibiting the activation of the inflammasome (71) ( Figure 3 )

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