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The low-MW fractions are pushed through the channels into the dermis, where they engage CD44 receptors on fibroblasts and contribute to volumetric hydration in deeper layers

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Med., 393 (7) (2025)

Tirzepatide may reduce the effectiveness of oral contraceptives due to delayed gastric emptying, making backup contraception important during dose changes (Eli Lilly and Company, 2024)

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