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It works by inhibiting the tyrosinase enzyme, which converts dark melanin (eumelanin) to lighter melanin (pheomelanin), resulting in gradual skin brightening and overall detoxification

For instance, acetaminophen (Tylenol) lowers glutathione levels as the liver uses its stores to metabolize this drug

Glutathione plays a crucial role in detoxifying harmful substances, maintaining the immune system, and regulating cellular processes

25 Hcy promotes glutathione (GSH) synthesis by entering the transsulfuration pathway or is converted back to methionine by methionine synthase (MTR/MS), accordingly completing the methionine cycle

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Therefore, the ratio of GSH and GSSG has been noted as index of oxidative stress