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The transmembrane region of RyRs follows a topology very similar to tetrameric voltage-gated channels, with 6 well-defined transmembrane helices per subunit (Fig

Neither glutathione trisulfide (GSSSG, a potent anti-oxidant) nor lipoic acid enhanced c-met binding or nitration resistance, and thus served as controls

The old cell 3-OM did not show an obvious increase of Nrf2 protein upon MB treatment probably due to its extreme senescent cell stage thus limited cells for the analysis

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