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Research Evidence Comparison# Retatrutide Research# Phase 1 : First-in-human study established safety and pharmacokinetics Phase 2 (n=338) : Published in NEJM (2023), demonstrated dose-dependent weight loss up to 24.2% at 48 weeks with 12 mg dose

It can be an issue on its own, or act as an underlying cause of numerous conditions

These medications work through entirely different mechanisms and are metabolised via separate pathways in the body