View Study [2]"Extracellular signal-regulated kinase and phosphoinositol-3 kinase mediate IGF-1 induced proliferation of fetal cardiomyocytes" Sundgren NC, Giraud GD, et al., 2003 Finding: Researchers found that Long R3 IGF-I stimulates cell proliferation (hyperplasia) through both ERK and PI3K signaling pathwaysthis explains the unique ability of IGF-1 to create new cells, not just make existing cells bigger
Systematic investigation of the underlying mechanisms of GLP-1 receptor agonists to prevent myocardial infarction in patients with type 2 diabetes mellitus using network pharmacology
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Despite the great success of traditional lipid-lowering treatments, such as PCSK9 inhibitors and statins, in lowering LDL-C and the chance of atherosclerotic cardiovascular disease, the distinct pathogenic mechanism of Lp(a) remains a major clinical management challenge
Cooperation between mitochondria and peroxisomes Previous studies in mammals and zebrafish have shown that when mitochondrial -oxidation is inhibited and fat accumulates in the liver or heart, CPT1 gene expression or enzyme activity compensatorily increases to enhance FA transport into the mitochondrial matrix ( Reference Li, Li and Qin 32 , Reference Degrace, Demizieux and Gresti 52 , Reference Degrace, Demizieux and Du 56 )
Speakers: Mr Alper AL, Dr Ceren Sezer T_05 ENVIRONMENT AND CLIMATE (B): Water Systems and Management A0-14 (YTU Davutpasa Campus) A0-14 YTU Davutpasa Campus Convener: Ethemcan Turhan (University of Groningen) 657 DESIGNING [FROM] THE SEA Challenges, methodologies and scenarios for planning with water Setting the context: global pressures/water challenges Cities are under pressure due to multiple and conflicting social, economic, and environmental challenges
