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Nevertheless, the effect of butyrate on human gut mucosa and immunity is well known and is key to human health 3,5,6,43

136 Similarly, circMETTL3-156aa, a novel peptide encoded by circMETTL3 derived from METTL3 in secondary hemophagocytic lymphohistiocytosis (sHLH) patient plasma exosomes, promotes M1 macrophage polarization by binding with LDHA and enhancing macrophage glycolysis

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